Instructions:

Develop a response to this question. Ensure you have answered all parts of the question completely. Complete this assignment described below using complete sentences in a paragraph format, and be sure to check your spelling when complete. 

Please read the Discussion Board Directions located on the course menu on the left side of the screen before you begin to post or reply.

Topic:

A list of specific types of transporters found in cell membranes is given below. Choose ONE of these and then describe in detail:

1. how the transporter works
2. whether it is an active or passive transporter
3. a specific type of cell that it can be found in and why it is important in this cell type
4. consequences for body function when this transporter type fails (due to a mutation that makes it non-functional).

Transporter types:

• Sodium/Potassium Pump (this one is quite straight forward so you should be able to give a very detailed description).
• GLUT transporters (choose one of these):
  • GLUT 1
  • GLUT 2
  • GLUT 3
  • GLUT 4
• Sodium/Glucose transporters in enterocytes
• Gated ion channels in the cochlea of the ear
• Voltage-gated Na+ channel
• Voltage-gated K+ channel
• Voltage-gated Ca+2 channel
• Chloride leak channels
• Hydrogen ion (H+) ATPase
• Dopamine transporter (DAT)
• Serotonin transporter
• Norepinephrine transporter

In some cases, you may be able to find a specific related disease. If you do not, think about why the transporter needs to be in the cell type you named and think about what would happen to the body if the transporter did not work.

Respond to Others: Many of the descriptions will be quite technical. It is your job to write the description for your transporter so that your classmates can easily understand it. This means you will probably have to look up quite a few terms and re-word them into “common” language. Compare and contrast the type of transporter you reviewed with those that others reviewed. Choose a transporter reviewed by another student and go into more depth on the mechanism by which it operates or the need for the transporter in the cell type in which it is found, and make corrections to another student’s post if they are incorrect about something they have posted. 

Discussion Board Grading Rubric:

1. Original posting: (7 points)

• Posting is at least 100 words, and has proper grammar and punctuation (2 points).
• Posting fully addresses the discussion board questions. (2 points)
• Discussion is original and at a critical level, not just recitation of facts. (2 points)
• Proper citation of references. (1 point)

2. Reply to peer discussion posts: (3 points)

• Discuss one point you like/agree with, and one point you dislike/disagree with and explain why. (2 points)
• Length of positing consists of approximately 100 words minimum. (1 point)

Please respond the this student’s answer.

Christine Piper Discussion Board 2

Serotonin is a neurotransmitter affecting multiple physiological processes and cognitive brain functions, among them mood and emotions, which is why it has been linked to mood disorders such as depression. The way a serotonin transporter works is a serotonin transporter is an integral membrane protein found in abundance in the human brain. It moves the neurotransmitter serotonin from the space between synapses, the synaptic cleft, into presynaptic neurons. In doing this, it terminates the action of the mood-stabilizing neurotransmitter and recycles it. The neurons in the brain communicate with each other using serotonin and similar substances. The presence of this particular protein regulates the concentraition of serotonin in the synapse, and changes or disruptions in the serotonin transporter system are shown to have major effects on various mental health issues. When serotonin is active outside our brain cells, we become nervours, unhappy or unable to eel any pleasure. One main function is to help people feel calm, aide in sleep, and maintain a healthy appetite. Consequeses or fail to function or those who suffer from low serotonin levels generally suffer from insomnia, depression, or both.