CHEM 3118: Synthetic Chemistry
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Over 144 million chemical substances are known, many of which possess a complex arrangement of atoms and bonds that lead to unique and intricate 3-dimensional structures. Chemical structure is directly related to the function of molecules. While the structures of many known compounds have been built using the limited set of reactions that are employed by Nature, not all chemical structures can be accessed this way. Synthetic chemists have developed a multitude of reactions and strategies to build molecules that can’t be accessed using Nature’s toolkit. These can be applied to the creation of manufactured chemicals that improve our everyday lives, including medicines, fabrics, coatings, and in food production. In this unit you will learn fundamental strategies and reactions that can be used to create new molecular structures. You will investigate strategies that allow the synthesis of specific isomers to interact with the chiral world we live in, including molecules that cure disease. You will learn modern synthetic reaction methods that mitigate the environmental impact of chemical synthesis. By doing this unit you will develop an understanding of how chemical bonds can be broken and formed in a directed manner to build new molecular architectures with specific properties and 3-dimensional shapes.
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