Health & Medical Coronary Artery Disease Research Paper

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Coronary Artery disease

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1- introduction about the disease

2-Coronary Artery circulation

3- Coronary Artery Pathophysiology


Coronary Artery disease
1. Introduction
a. Statistics and fact of coronary artery disease
b. Coronary circulation ( Rehman S, Khan A, 2020)
2. Coronary Artery disease: Pathophysiology
a. Atherosclerosis (Libby P, and Theroux. 2005.)
b. Risk factors
i. High and low LDL cholesterol
ii. High blood pressure
iii. Diabetes
iv. Smoking
v. Age
vi. Obesity
3. Treatment (Mayo Clinic: Coronary artery disease)
a. Lifestyle Changes
i. Eat healthy foods, exercise regularly and Quit smoking
ii. Control weight, blood pressure and cholesterol
iii. Keep diabetes under control and reduce stress
b. Drugs Treatment
i. Beta blockers
ii. Calcium channel blockers
iii. Ranolazine
iv. Nitrates
v. Nitroglycerin
vi. Angiotensin-converting enzyme (ACE) inhibitors
1. Boudonas G. E. (2010). β-Blockers in coronary artery disease management. Hippokratia, 14(4),
231–235. Collet, C., Capodanno, D., Onuma, Y. et al. Left main coronary artery disease:
pathophysiology, diagnosis, and treatment. Nat Rev Cardiol 15, 321–331 (2018).
2. Price JF, MowbrayPI, Lee AJ, Rumley A, Lowe G, and Fowkes FG. Relationship Between Smoking
and Cardiovascular Risk Factors in the Development of Peripheral Arterial Disease and Coronary
Artery Disease; Edinburgh Artery Study. European Heart Journal, 1999/20,5/P 344–353,
3. Libby P, and Theroux. Pathophysiology of Coronary Artery Disease. Circulation. 2005;111:3481–
4. Judy WM. and Cheng. Ranolazine for the management of coronary artery disease, Clinical
Therapeutics, 2006, 0149-2918, P: 1996-2007.
5. Jespersen L, Hvelplund A, Steen A, Frants P, Galatius S, Jan K. Madsen, Jørgensen E, Kelbæk H,
and Eva P. Stable Angina Pectoris with no Obstructive Coronary Artery Disease is associated with
increased risks of major adverse cardiovascular events. European Heart Journal, 2012, 33, P734–
6. NATIONAL HEART, LUNG, AND BLOOD INSTITUTE. Coronary Heart Disease:,the%20surface%20of%20the%20heart
7. Weightman, M. MBChB, Gibbs, M. MBBS, FANZCA, MD; Sheminant, RN, Eric G, Mahon, Barry D,
and et al. Drug Therapy Before Coronary Artery Surgery: Nitrates Are Independent Predictors of
Mortality and beta-Adrenergic Blockers Predict Survival. Anesthesia & Analgesia. 1999,88, 2. P:
286-291 doi: 10.1213/00000539-199902000-00011
8. Rehman S, Khan A, Rehman A. Physiology, Coronary Circulation.. In: StatPearls [Internet].
Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from:
9. Centers for Disease Control and Prevention 2020. Heart Disease Facts.

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