Statistically Significant vs. Clinically Significant

Evidence-based practice is expected to affect the clinical decision-making of healthcare providers, but interpreting research is often difficult for some clinicians. Interpretation of clinical research is important in that it affects the clinical decision-making affecting patient safety, quality of care, and efficacy among other areas. Narrowing down, one of the common challenges faced by clinicians or readers is interpreting the word “significance.” According to Ranganathan, Pramesh, and Buyse (2015), the term clinically significant is often confused and misinterpreted with the word clinically important. The confusion emanates from the fact that people usually interpret significance in this case to literally mean important. However, when applied statistically, the word has a more restrictive connotation. In clinical practice, the word statistical significance implies the reliability of the study results, which is measured using the “P0″ values versus confidence intervals. Virtually, statistical significance quantifies the probability of a study results based on chance. On the other hand, clinical significance encompasses the magnitude of the actual treatment effect. It involves the ability f the study results to impact the current clinical practice. 

Beyond the traditional testing of statistical significance, statistical significance is used to answer questions of probability to determine if a hypothesis can be accepted or rejected. Statistical significance provides important insights into levels of probability and to ensure that the null hypothesis is not rejected incorrectly. However, as Page (2014) elaborate, statistical significance cannot be used to provide clinical insight in important variables. Instead, it is clinical significance that provides important insight into variables such as treatment effect size, magnitude of change, or direction of the outcome.

Don't use plagiarized sources. Get Your Custom Essay on
Statistically Significant vs. Clinically Significant
Just from $13/Page
Order Essay


Page, P. (2014). Beyond statistical significance: clinical interpretation of rehabilitation research literature. International Journal of Sports Physical Therapy, 9(5), 726-36.Ranganathan, P., Pramesh, C. S., & Buyse, M. (2015). Common pitfalls in statistical analysis: Clinical versus statistical significance. Perspectives in Clinical Research, 6(3), 169-170.

Place your order
(550 words)

Approximate price: $22

Calculate the price of your order

550 words
We'll send you the first draft for approval by September 11, 2018 at 10:52 AM
Total price:
The price is based on these factors:
Academic level
Number of pages
Basic features
  • Free title page and bibliography
  • Unlimited revisions
  • Plagiarism-free guarantee
  • Money-back guarantee
  • 24/7 support
On-demand options
  • Writer’s samples
  • Part-by-part delivery
  • Overnight delivery
  • Copies of used sources
  • Expert Proofreading
Paper format
  • 275 words per page
  • 12 pt Arial/Times New Roman
  • Double line spacing
  • Any citation style (APA, MLA, Chicago/Turabian, Harvard)

Our guarantees

Delivering a high-quality product at a reasonable price is not enough anymore.
That’s why we have developed 5 beneficial guarantees that will make your experience with our service enjoyable, easy, and safe.

Money-back guarantee

You have to be 100% sure of the quality of your product to give a money-back guarantee. This describes us perfectly. Make sure that this guarantee is totally transparent.

Read more

Zero-plagiarism guarantee

Each paper is composed from scratch, according to your instructions. It is then checked by our plagiarism-detection software. There is no gap where plagiarism could squeeze in.

Read more

Free-revision policy

Thanks to our free revisions, there is no way for you to be unsatisfied. We will work on your paper until you are completely happy with the result.

Read more

Privacy policy

Your email is safe, as we store it according to international data protection rules. Your bank details are secure, as we use only reliable payment systems.

Read more

Fair-cooperation guarantee

By sending us your money, you buy the service we provide. Check out our terms and conditions if you prefer business talks to be laid out in official language.

Read more
Live Chat+1(978) 822-0999EmailWhatsApp

Order your essay today and save 20% with the discount code LEMONADE