UWI Open Campus St Vincent Quality Control and Laboratory Management Worksheet

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Please complete the Chemical Inventory. The three safety data sheets for the chemicals listed on the inventory have been provided below. Once you have completed the inventory, please upload your document using the submission link in this assignment.

Example inventory sheet is attached “Chemical Inventory Example”

Chemical Inventory Homework Assignment:

Safety Data Sheets for the following chemicals will be sent directly to the tutor once bid is accepted.

hydrochloric-acid-concentrate-certified-acs-fisher-chemical.pdf

propylene-oxide-reagent-fisher-chemical.pdf

reagent alcohol (ethyl).pdf

2022 CHEMICAL INVENTORY
Department of Pathology, Immunohistochemistry Laboratory / West Bldg Room 205
Location:
CHEMICALS CABINET
Chemical
CAS #
Vendor
Calcium Chloride
10043-52-4
Cupric Sulfate
Toxicity
Chronic (C)
Health Hazard Flammable Reactivity Carcinogen or Acute (A)
Reproductive
Toxicity
PPE
Blue
Red
Yelow
Lab coat for all
Fisher
2
0
1
Gloves/Lab coat
7758-98-7
Fisher
2
0
1
DAKO TBS
None
DAKO
2
0
2
Gloves/Lab coat
Fast Green
2353-45-9
Sigma
3
0
0
Gloves/Lab coat/Safety glasses/Respirator
Trizma Base
201-064-4
Sigma
0
0
0
Gloves/Lab coat
Trizma Hydrochloride
1185-53-1
Sigma
2
0
0
Gloves/Lab coat
Tween 20
None
Dako
0
0
0
Gloves/Lab coat
WARNING: If
accidental contact
occurs refer to SDS,
Call EHS 243-0000
and Contact
Pathology
Administrator 5851234
Note** Decant/pour all hazardous chemicals as specified in MSDS.
UPDATED: 1/2/2019 ABC
No
Hazard Rating:
0 Minimal
1 Slight
2 Moderate
3 Serious
4 Severe
(A)
No
Gloves/Lab coat/Safety glasses/Respirator
2022 CHEMICAL INVENTORY
Department of Pathology, Immunohistochemistry Laboratory / West Bldg Room 205
Location:
CHEMICALS CABINET
Chemical
CAS #
Vendor
Calcium Chloride
10043-52-4
Cupric Sulfate
Toxicity
Chronic (C)
Health Hazard Flammable Reactivity Carcinogen or Acute (A)
Reproductive
Toxicity
PPE
Blue
Red
Yelow
Lab coat for all
Fisher
2
0
1
Gloves/Lab coat
7758-98-7
Fisher
2
0
1
DAKO TBS
None
DAKO
2
0
2
Gloves/Lab coat
Fast Green
2353-45-9
Sigma
3
0
0
Gloves/Lab coat/Safety glasses/Respirator
Trizma Base
201-064-4
Sigma
0
0
0
Gloves/Lab coat
Trizma Hydrochloride
1185-53-1
Sigma
2
0
0
Gloves/Lab coat
Tween 20
None
Dako
0
0
0
Gloves/Lab coat
WARNING: If
accidental contact
occurs refer to SDS,
Call EHS 243-0000
and Contact
Pathology
Administrator 5851234
Note** Decant/pour all hazardous chemicals as specified in MSDS.
UPDATED: 1/2/2019 ABC
No
Hazard Rating:
0 Minimal
1 Slight
2 Moderate
3 Serious
4 Severe
(A)
No
Gloves/Lab coat/Safety glasses/Respirator
2022 CHEMICAL INVENTORY
Department of Pathology, Immunohistochemistry Laboratory / West Bldg Room 205
Location:
CHEMICALS CABINET
Chemical
CAS #
Vendor
Calcium Chloride
10043-52-4
Cupric Sulfate
Toxicity
Chronic (C)
Health Hazard Flammable Reactivity Carcinogen or Acute (A)
Reproductive
Toxicity
PPE
Blue
Red
Yelow
Lab coat for all
Fisher
2
0
1
Gloves/Lab coat
7758-98-7
Fisher
2
0
1
DAKO TBS
None
DAKO
2
0
2
Gloves/Lab coat
Fast Green
2353-45-9
Sigma
3
0
0
Gloves/Lab coat/Safety glasses/Respirator
Trizma Base
201-064-4
Sigma
0
0
0
Gloves/Lab coat
Trizma Hydrochloride
1185-53-1
Sigma
2
0
0
Gloves/Lab coat
Tween 20
None
Dako
0
0
0
Gloves/Lab coat
WARNING: If
accidental contact
occurs refer to SDS,
Call EHS 243-0000
and Contact
Pathology
Administrator 5851234
Note** Decant/pour all hazardous chemicals as specified in MSDS.
UPDATED: 1/2/2019 ABC
No
Hazard Rating:
0 Minimal
1 Slight
2 Moderate
3 Serious
4 Severe
(A)
No
Gloves/Lab coat/Safety glasses/Respirator
CHEMICAL INVENTORY EXERCISE
Hazard Communication Standard or “Right to Know” Standard
Name of Institution:
Location:
Listed below are chemicals which are a health hazard, flammable, reactive, carcinogenic or toxic.
Chemical Name
CAS #
Vendor
Health
Hazard
Blue
Flammable
Red
Reactivity
Yelow
Carcinogen
Toxicity
Chronic (C) or
Acute (A)
Hazard Rating:
NOTE
Reproductive
Toxicity
Hydrochloric Acid
Reagent Alchol (Ethyl)
Propylene Oxide
Note** Decant/pour
all hazardous
chemicals as
specified in MSDS.
WARNING: If accidental
contact occurs refer to
SDS, Call EHS 243-0000
and Contact Pathology
Administrator 585-1234
UPDATED: 09/09/2019
0 Minimal
1 Slight
2 Moderate
3 Serious
4 Severe
n/a = not applicable
PPE
CHEMICAL INVENTORY EXERCISE
Hazard Communication Standard or “Right to Know” Standard
Name of Institution:
Location:
Listed below are chemicals which are a health hazard, flammable, reactive, carcinogenic or toxic.
Chemical Name
CAS #
Vendor
Health
Hazard
Blue
Flammable
Red
Reactivity
Yelow
Carcinogen
Toxicity
Chronic (C) or
Acute (A)
Hazard Rating:
NOTE
Reproductive
Toxicity
Hydrochloric Acid
Reagent Alchol (Ethyl)
Propylene Oxide
Note** Decant/pour
all hazardous
chemicals as
specified in MSDS.
WARNING: If accidental
contact occurs refer to
SDS, Call EHS 243-0000
and Contact Pathology
Administrator 585-1234
UPDATED: 09/09/2019
0 Minimal
1 Slight
2 Moderate
3 Serious
4 Severe
n/a = not applicable
PPE
SIGMA-ALDRICH
sigma-aldrich.com
SAFETY DATA SHEET
Version 5.8
Revision Date 09/23/2016
Print Date 02/25/2018
1. PRODUCT AND COMPANY IDENTIFICATION
1.1
1.2
Product identifiers
Product name
:
Reagent alcohol
Product Number
Brand
:
:
362808
Aldrich
CAS-No.
:
64-17-5
Relevant identified uses of the substance or mixture and uses advised against
Identified uses
1.3
1.4
:
Laboratory chemicals, Synthesis of substances
Details of the supplier of the safety data sheet
Company
:
Sigma-Aldrich
3050 Spruce Street
SAINT LOUIS MO 63103
USA
Telephone
Fax
:
:
+1 800-325-5832
+1 800-325-5052
Emergency telephone number
Emergency Phone #
:
+1-703-527-3887 (CHEMTREC)
2. HAZARDS IDENTIFICATION
2.1
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Flammable liquids (Category 2), H225
Acute toxicity, Oral (Category 4), H302
Eye irritation (Category 2A), H319
Specific target organ toxicity – single exposure (Category 1), H370
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2
GHS Label elements, including precautionary statements
Pictogram
Signal word
Danger
Hazard statement(s)
H225
H302
H319
H370
Highly flammable liquid and vapour.
Harmful if swallowed.
Causes serious eye irritation.
Causes damage to organs.
Precautionary statement(s)
P210
P233
P240
P241
P242
Keep away from heat/sparks/open flames/hot surfaces. No smoking.
Keep container tightly closed.
Ground/bond container and receiving equipment.
Use explosion-proof electrical/ ventilating/ lighting/ equipment.
Use only non-sparking tools.
Aldrich – 362808
Page 1 of 11
P243
P260
P264
P270
P280
P301 + P312 + P330
Take precautionary measures against static discharge.
Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
Wash skin thoroughly after handling.
Do not eat, drink or smoke when using this product.
Wear protective gloves/ eye protection/ face protection.
IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
Rinse mouth.
IF ON SKIN (or hair): Take off immediately all contaminated clothing.
Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
IF exposed: Call a POISON CENTER or doctor/ physician.
If eye irritation persists: Get medical advice/ attention.
In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to
extinguish.
Store in a well-ventilated place. Keep cool.
Store locked up.
Dispose of contents/ container to an approved waste disposal plant.
P303 + P361 + P353
P305 + P351 + P338
P307 + P311
P337 + P313
P370 + P378
P403 + P235
P405
P501
2.3
Hazards not otherwise classified (HNOC) or not covered by GHS – none
3. COMPOSITION/INFORMATION ON INGREDIENTS
3.2
Mixtures
Synonyms
:
Absolute alcohol
Ethyl alcohol, Reagent alcohol
Formula
Molecular weight
:
:
C2H6O
46.07 g/mol
Hazardous components
Component
Classification
Concentration
Ethanol
CAS-No.
EC-No.
Index-No.
64-17-5
200-578-6
603-002-00-5
Flam. Liq. 2; Eye Irrit. 2A;
H225, H319
>= 90 – = 5 – < 10 % 2-Propanol CAS-No. EC-No. Index-No. 67-63-0 200-661-7 603-117-00-0 Flam. Liq. 2; Eye Irrit. 2A; STOT SE 3; H225, H319, H336 >= 5 – < 10 % For the full text of the H-Statements mentioned in this Section, see Section 16. 4. FIRST AID MEASURES 4.1 Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. Aldrich - 362808 Page 2 of 11 In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. 4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 4.3 Indication of any immediate medical attention and special treatment needed No data available 5. FIREFIGHTING MEASURES 5.1 Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. 5.2 Special hazards arising from the substance or mixture No data available 5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary. 5.4 Further information Use water spray to cool unopened containers. 6. ACCIDENTAL RELEASE MEASURES 6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8. 6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. 6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13). 6.4 Reference to other sections For disposal see section 13. 7. HANDLING AND STORAGE 7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Use explosion-proof equipment.Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2. 7.2 Conditions for safe storage, including any incompatibilities Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Moisture sensitive. Handle and store under inert gas. 7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated Aldrich - 362808 Page 3 of 11 8. EXPOSURE CONTROLS/PERSONAL PROTECTION 8.1 Control parameters Components with workplace control parameters Component CAS-No. Value Control parameters Ethanol 64-17-5 TWA 1,000.000000 ppm Remarks Methanol 67-56-1 Basis USA. ACGIH Threshold Limit Values (TLV) Upper Respiratory Tract irritation Confirmed animal carcinogen with unknown relevance to humans TWA 1,000 ppm USA. OSHA - TABLE Z-1 Limits for 1,900 mg/m3 Air Contaminants - 1910.1000 TWA 1,000 ppm USA. Occupational Exposure Limits 1,900 mg/m3 (OSHA) - Table Z-1 Limits for Air Contaminants The value in mg/m3 is approximate. TWA 1,000.000000 USA. Occupational Exposure Limits ppm (OSHA) - Table Z-1 Limits for Air 1,900.000000 Contaminants mg/m3 The value in mg/m3 is approximate. TWA 1,000.000000 USA. NIOSH Recommended ppm Exposure Limits 1,900.000000 mg/m3 STEL 1,000.000000 USA. ACGIH Threshold Limit Values ppm (TLV) Upper Respiratory Tract irritation Confirmed animal carcinogen with unknown relevance to humans TWA 200.000000 USA. ACGIH Threshold Limit Values ppm (TLV) Headache Nausea Dizziness Eye damage Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Danger of cutaneous absorption STEL 250.000000 USA. ACGIH Threshold Limit Values ppm (TLV) Headache Nausea Dizziness Eye damage Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Danger of cutaneous absorption TWA 200.000000 USA. NIOSH Recommended ppm Exposure Limits 260.000000 mg/m3 Potential for dermal absorption Aldrich - 362808 Page 4 of 11 ST 250.000000 USA. NIOSH Recommended ppm Exposure Limits 325.000000 mg/m3 Potential for dermal absorption TWA 200.000000 USA. Occupational Exposure Limits ppm (OSHA) - Table Z-1 Limits for Air 260.000000 Contaminants mg/m3 The value in mg/m3 is approximate. TWA 200 ppm USA. ACGIH Threshold Limit Values (TLV) Headache Nausea Dizziness Eye damage Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Danger of cutaneous absorption STEL 250 ppm USA. ACGIH Threshold Limit Values (TLV) Headache Nausea Dizziness Eye damage Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Danger of cutaneous absorption TWA 200 ppm USA. NIOSH Recommended 260 mg/m3 Exposure Limits Potential for dermal absorption ST 250 ppm USA. NIOSH Recommended 325 mg/m3 Exposure Limits Potential for dermal absorption TWA 200 ppm USA. Occupational Exposure Limits 260 mg/m3 (OSHA) - Table Z-1 Limits for Air Contaminants The value in mg/m3 is approximate. STEL 250 ppm USA. OSHA - TABLE Z-1 Limits for 325 mg/m3 Air Contaminants - 1910.1000 Skin notation TWA 200 ppm USA. OSHA - TABLE Z-1 Limits for 260 mg/m3 Air Contaminants - 1910.1000 Skin notation C 1,000 ppm California permissible exposure limits for chemical contaminants (Title 8, Article 107) Skin PEL 200 ppm California permissible exposure 260 mg/m3 limits for chemical contaminants (Title 8, Article 107) Skin STEL 250 ppm California permissible exposure 325 mg/m3 limits for chemical contaminants (Title 8, Article 107) Skin Aldrich - 362808 Page 5 of 11 2-Propanol 67-63-0 TWA 200.000000 ppm USA. ACGIH Threshold Limit Values (TLV) Central Nervous System impairment Upper Respiratory Tract irritation Eye irritation Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Not classifiable as a human carcinogen TWA 200 ppm USA. ACGIH Threshold Limit Values (TLV) Central Nervous System impairment Upper Respiratory Tract irritation Eye irritation Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Not classifiable as a human carcinogen STEL 400 ppm USA. ACGIH Threshold Limit Values (TLV) Central Nervous System impairment Upper Respiratory Tract irritation Eye irritation Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Not classifiable as a human carcinogen STEL 400.000000 USA. ACGIH Threshold Limit Values ppm (TLV) Central Nervous System impairment Upper Respiratory Tract irritation Eye irritation Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Not classifiable as a human carcinogen TWA 400.000000 USA. Occupational Exposure Limits ppm (OSHA) - Table Z-1 Limits for Air 980.000000 Contaminants mg/m3 The value in mg/m3 is approximate. TWA 400.000000 USA. NIOSH Recommended ppm Exposure Limits 980.000000 mg/m3 ST 500.000000 USA. NIOSH Recommended ppm Exposure Limits 1,225.000000 mg/m3 PEL 400 ppm California permissible exposure 980 mg/m3 limits for chemical contaminants (Title 8, Article 107) STEL 500 ppm California permissible exposure 1,225 mg/m3 limits for chemical contaminants (Title 8, Article 107) Biological occupational exposure limits Component CAS-No. Parameters Methanol Aldrich - 362808 67-56-1 Methanol Value Biological specimen Basis 15.0000 mg/l Urine ACGIH - Biological Exposure Indices (BEI) Page 6 of 11 Remarks 2-Propanol 8.2 67-63-0 End of shift (As soon as possible after exposure ceases) Methanol 15 mg/l Urine ACGIH - Biological Exposure Indices (BEI) End of shift (As soon as possible after exposure ceases) Acetone 40.0000 Urine ACGIH - Biological mg/l Exposure Indices (BEI) End of shift at end of workweek Exposure controls Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Personal protective equipment Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Full contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 480 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.2 mm Break through time: 30 min Material tested:Dermatril® P (KCL 743 / Aldrich Z677388, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multipurpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. 9. PHYSICAL AND CHEMICAL PROPERTIES 9.1 Information on basic physical and chemical properties a) Appearance Form: liquid b) Odour No data available Aldrich - 362808 Page 7 of 11 9.2 c) Odour Threshold No data available d) pH No data available e) Melting point/freezing point Melting point/range: -130 °C (-202 °F) f) Initial boiling point and boiling range 78 °C (172 °F) at 1,013 hPa (760 mmHg) g) Flash point 9 °C (48 °F) - closed cup h) Evaporation rate No data available i) Flammability (solid, gas) No data available j) Upper/lower flammability or explosive limits Upper explosion limit: 24.5 %(V) Lower explosion limit: 3.3 %(V) k) Vapour pressure 59.5 hPa (44.6 mmHg) at 20 °C (68 °F) l) Vapour density No data available m) Relative density 0.785 g/cm3 n) Water solubility No data available o) Partition coefficient: noctanol/water No data available p) Auto-ignition temperature 362 °C (684 °F) q) Decomposition temperature No data available r) Viscosity No data available s) Explosive properties No data available t) Oxidizing properties No data available Other safety information No data available 10. STABILITY AND REACTIVITY 10.1 Reactivity No data available 10.2 Chemical stability Stable under recommended storage conditions. 10.3 Possibility of hazardous reactions Vapours may form explosive mixture with air. 10.4 Conditions to avoid Heat, flames and sparks. 10.5 Incompatible materials Aluminium, Acids, Oxidizing agents, Alkali metals, Halogenated compounds, Ammonia, Acid chlorides, Acid anhydrides, Reducing agents, Peroxides 10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides Other decomposition products - No data available In the event of fire: see section 5 Aldrich - 362808 Page 8 of 11 11. TOXICOLOGICAL INFORMATION 11.1 Information on toxicological effects Acute toxicity No data available Inhalation: No data available Dermal: No data available No data available Skin corrosion/irritation No data available Serious eye damage/eye irritation No data available Respiratory or skin sensitisation No data available Germ cell mutagenicity No data available Carcinogenicity IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. NTP: No component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP. OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA. Reproductive toxicity No data available No data available Specific target organ toxicity - single exposure No data available Specific target organ toxicity - repeated exposure No data available Aspiration hazard No data available Additional Information RTECS: Not available To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated., Central nervous system depression, Gastrointestinal disturbance, Nausea, Dizziness, Headache, narcosis, May cause convulsions. Stomach - Irregularities - Based on Human Evidence Kidney - Irregularities - Based on Human Evidence Stomach - Irregularities - Based on Human Evidence (Ethanol) Stomach - Irregularities - Based on Human Evidence (Methanol) Kidney - Irregularities - Based on Human Evidence (2-Propanol) 12. ECOLOGICAL INFORMATION 12.1 Toxicity No data available 12.2 Persistence and degradability No data available Aldrich - 362808 Page 9 of 11 12.3 Bioaccumulative potential No data available 12.4 Mobility in soil No data available 12.5 Results of PBT and vPvB assessment PBT/vPvB assessment not available as chemical safety assessment not required/not conducted 12.6 Other adverse effects No data available 13. DISPOSAL CONSIDERATIONS 13.1 Waste treatment methods Product Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Contaminated packaging Dispose of as unused product. 14. TRANSPORT INFORMATION DOT (US) UN number: 1170 Class: 3 Proper shipping name: Ethanol solutions Reportable Quantity (RQ): Packing group: II Poison Inhalation Hazard: No IMDG UN number: 1170 Class: 3 Proper shipping name: ETHANOL SOLUTION Packing group: II IATA UN number: 1170 Class: 3 Proper shipping name: Ethanol solution Packing group: II EMS-No: F-E, S-D 15. REGULATORY INFORMATION SARA 302 Components No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302. SARA 313 Components The following components are subject to reporting levels established by SARA Title III, Section 313: CAS-No. Revision Date Methanol 67-56-1 2007-07-01 2-Propanol 67-63-0 1987-01-01 SARA 311/312 Hazards Fire Hazard, Acute Health Hazard, Chronic Health Hazard Massachusetts Right To Know Components Ethanol Methanol 2-Propanol CAS-No. 64-17-5 67-56-1 67-63-0 Revision Date 2007-03-01 2007-07-01 1987-01-01 CAS-No. 64-17-5 67-56-1 67-63-0 Revision Date 2007-03-01 2007-07-01 1987-01-01 Pennsylvania Right To Know Components Ethanol Methanol 2-Propanol Aldrich - 362808 Page 10 of 11 New Jersey Right To Know Components Ethanol Methanol 2-Propanol California Prop. 65 Components WARNING: This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. Methanol CAS-No. 64-17-5 67-56-1 67-63-0 Revision Date 2007-03-01 2007-07-01 1987-01-01 CAS-No. 67-56-1 Revision Date 2012-03-16 16. OTHER INFORMATION Full text of H-Statements referred to under sections 2 and 3. Acute Tox. Eye Irrit. Flam. Liq. H225 H301 + H311 + H331 H302 H319 H336 H370 STOT SE Acute toxicity Eye irritation Flammable liquids Highly flammable liquid and vapour. Toxic if swallowed, in contact with skin or if inhaled Harmful if swallowed. Causes serious eye irritation. May cause drowsiness or dizziness. Causes damage to organs. Specific target organ toxicity - single exposure HMIS Rating Health hazard: Chronic Health Hazard: Flammability: Physical Hazard 2 * 3 0 NFPA Rating Health hazard: Fire Hazard: Reactivity Hazard: 2 3 0 Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale. Preparation Information Sigma-Aldrich Corporation Product Safety – Americas Region 1-800-521-8956 Version: 5.8 Aldrich - 362808 Revision Date: 09/23/2016 Print Date: 02/25/2018 Page 11 of 11 SAFETY DATA SHEET Creation Date 15-Feb-2010 Revision Date 18-Jan-2018 Revision Number 3 1. Identification Product Name Hydrochloric acid solution, 1N Cat No. : SA55; S748561 Synonyms Muriatic acid solution; Hydrogen chloride solution (Certified) Recommended Use Uses advised against Laboratory chemicals. Not for food, drug, pesticide or biocidal product use Details of the supplier of the safety data sheet Company Fisher Scientific One Reagent Lane Fair Lawn, NJ 07410 Tel: (201) 796-7100 Emergency Telephone Number CHEMTRECÒ, Inside the USA: 800-424-9300 CHEMTRECÒ, Outside the USA: 001-703-527-3887 2. Hazard(s) identification Classification This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) Corrosive to metals Skin Corrosion/irritation Serious Eye Damage/Eye Irritation Category 1 Category 2 Category 1 Label Elements Signal Word Danger Hazard Statements May be corrosive to metals Causes skin irritation Causes serious eye damage ______________________________________________________________________________________________ Page 1 / 7 Revision Date 18-Jan-2018 Hydrochloric acid solution, 1N ______________________________________________________________________________________________ Precautionary Statements Prevention Keep only in original container Wear eye/face protection Wear protective gloves Wash face, hands and any exposed skin thoroughly after handling Skin IF ON SKIN: Wash with plenty of soap and water Take off contaminated clothing and wash before reuse If skin irritation occurs: Get medical advice/attention Eyes IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing Immediately call a POISON CENTER or doctor/physician Storage Store in corrosive resistant polypropylene container with a resistant inliner Disposal Dispose of contents/container to an approved waste disposal plant Hazards not otherwise classified (HNOC) None identified 3. Composition/Information on Ingredients Component Water Hydrochloric acid CAS-No 7732-18-5 7647-01-0 Weight % 96.35 3.65 4. First-aid measures General Advice If symptoms persist, call a physician. Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required. Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Obtain medical attention. Inhalation Move to fresh air. If breathing is difficult, give oxygen. Obtain medical attention. Ingestion Do not induce vomiting. Obtain medical attention. Most important symptoms and effects Notes to Physician May cause skin irritation and/or dermatitis. Suitable Extinguishing Media Substance is nonflammable; use agent most appropriate to extinguish surrounding fire. Unsuitable Extinguishing Media No information available Treat symptomatically 5. Fire-fighting measures Flash Point Method - Not applicable No information available No information available Autoignition Temperature Explosion Limits No data available Upper No data available Lower Sensitivity to Mechanical Impact No information available ______________________________________________________________________________________________ Page 2 / 7 Revision Date 18-Jan-2018 Hydrochloric acid solution, 1N ______________________________________________________________________________________________ Sensitivity to Static Discharge No information available Specific Hazards Arising from the Chemical Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Keep product and empty container away from heat and sources of ignition. Hazardous Combustion Products Hydrogen chloride gas Thermal decomposition can lead to release of irritating gases and vapors Protective Equipment and Precautions for Firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. NFPA Health 2 Flammability 0 Instability 0 Physical hazards N/A 6. Accidental release measures Use personal protective equipment. Ensure adequate ventilation. Do not get in eyes, on skin, or on clothing. Avoid release to the environment. See Section 12 for additional ecological information. Personal Precautions Environmental Precautions Methods for Containment and Clean Soak up with inert absorbent material. Keep in suitable, closed containers for disposal. Up 7. Handling and storage Handling Wear personal protective equipment. Ensure adequate ventilation. Do not get in eyes, on skin, or on clothing. Avoid ingestion and inhalation. Storage Keep containers tightly closed in a dry, cool and well-ventilated place. Corrosives area. 8. Exposure controls / personal protection Exposure Guidelines Component Hydrochloric acid ACGIH TLV Ceiling: 2 ppm OSHA PEL Ceiling: 5 ppm Ceiling: 7 mg/m3 (Vacated) Ceiling: 5 ppm (Vacated) Ceiling: 7 mg/m3 NIOSH IDLH IDLH: 50 ppm Ceiling: 5 ppm Ceiling: 7 mg/m3 Mexico OEL (TWA) Ceiling: 5 ppm Ceiling: 7 mg/m3 Legend ACGIH - American Conference of Governmental Industrial Hygienists NIOSH IDLH: The National Institute for Occupational Safety and Health Immediately Dangerous to Life or Health Engineering Measures Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations and safety showers are close to the workstation location. Personal Protective Equipment Eye/face Protection Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin and body protection Wear appropriate protective gloves and clothing to prevent skin exposure. Respiratory Protection Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard ______________________________________________________________________________________________ Page 3 / 7 Revision Date 18-Jan-2018 Hydrochloric acid solution, 1N ______________________________________________________________________________________________ EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Handle in accordance with good industrial hygiene and safety practice. Hygiene Measures 9. Physical and chemical properties Liquid Clear pungent No information available 1.1 (0.1N) 0 °C / 32 °F 100 °C / 212 °F Not applicable No information available Not applicable Physical State Appearance Odor Odor Threshold pH Melting Point/Range Boiling Point/Range Flash Point Evaporation Rate Flammability (solid,gas) Flammability or explosive limits Upper Lower Vapor Pressure Vapor Density Specific Gravity Solubility Partition coefficient; n-octanol/water Autoignition Temperature Decomposition Temperature Viscosity Molecular Formula Molecular Weight No data available No data available No information available No information available 1.0 - 1.2 Soluble in water No data available No information available No information available No information available HCl 36.46 10. Stability and reactivity Reactive Hazard None known, based on information available Stability Stable under normal conditions. Conditions to Avoid Incompatible products. Excess heat. Incompatible Materials Metals, Oxidizing agents, Reducing agents, Aldehydes Hazardous Decomposition Products Hydrogen chloride gas, Thermal decomposition can lead to release of irritating gases and vapors Hazardous Polymerization Hazardous polymerization does not occur. Hazardous Reactions None under normal processing. 11. Toxicological information Acute Toxicity Product Information Oral LD50 Dermal LD50 Vapor LC50 Component Information Component Water Hydrochloric acid Based on ATE data, the classification criteria are not met. ATE > 2000 mg/kg.
Based on ATE data, the classification criteria are not met. ATE > 2000 mg/kg.
Based on ATE data, the classification criteria are not met. ATE > 20 mg/l.
LD50 Oral
238 – 277 mg/kg ( Rat )
LD50 Dermal
Not listed
> 5010 mg/kg ( Rabbit )
LC50 Inhalation
Not listed
1.68 mg/L ( Rat ) 1 h
______________________________________________________________________________________________
Page 4 / 7
Revision Date 18-Jan-2018
Hydrochloric acid solution, 1N
______________________________________________________________________________________________
No information available
Toxicologically Synergistic
Products
Delayed and immediate effects as well as chronic effects from short and long-term exposure
Irritation
Causes eye burns; Irritating to skin
Sensitization
No information available
Carcinogenicity
The table below indicates whether each agency has listed any ingredient as a carcinogen.
Component
CAS-No
IARC
Water
7732-18-5
Not listed
Hydrochloric acid
7647-01-0
Not listed
IARC: (International Agency for Research on Cancer)
NTP
ACGIH
OSHA
Not listed
Not listed
Not listed
Not listed
Not listed
Not listed
IARC: (International Agency for Research on Cancer)
Group 1 – Carcinogenic to Humans
Group 2A – Probably Carcinogenic to Humans
Group 2B – Possibly Carcinogenic to Humans
Mutagenic Effects
Mutagenic effects have occured in microorganisms.
Reproductive Effects
Experiments have shown reproductive toxicity effects on laboratory animals.
Developmental Effects
Developmental effects have occurred in experimental animals.
Teratogenicity
Teratogenic effects have occurred in experimental animals.
STOT – single exposure
STOT – repeated exposure
None known
None known
Aspiration hazard
No information available
Mexico
Not listed
Not listed
Symptoms / effects,both acute and No information available
delayed
Endocrine Disruptor Information
No information available
Other Adverse Effects
See actual entry in RTECS for complete information.
12. Ecological information
Ecotoxicity
.
Component
Hydrochloric acid
Freshwater Algae

Freshwater Fish
282 mg/L LC50 96 h
Gambusia affinis
mg/L LC50 48 h Leucscus
idus
Microtox

Water Flea
56mg/L EC50 72h Daphnia
Persistence and Degradability
Soluble in water Persistence is unlikely based on information available.
Bioaccumulation/ Accumulation
No information available.
Mobility
Will likely be mobile in the environment due to its water solubility.
Waste Disposal Methods
Chemical waste generators must determine whether a discarded chemical is classified as a
hazardous waste. Chemical waste generators must also consult local, regional, and
national hazardous waste regulations to ensure complete and accurate classification.
13. Disposal considerations
14. Transport information
DOT
UN-No
UN1789
______________________________________________________________________________________________
Page 5 / 7
Revision Date 18-Jan-2018
Hydrochloric acid solution, 1N
______________________________________________________________________________________________
HYDROCHLORIC ACID SOLUTION
8
III
Proper Shipping Name
Hazard Class
Packing Group
TDG
UN-No
Proper Shipping Name
Hazard Class
Packing Group
IATA
UN-No
Proper Shipping Name
Hazard Class
Packing Group
IMDG/IMO
UN-No
Proper Shipping Name
Hazard Class
Packing Group
UN1789
HYDROCHLORIC ACID SOLUTION
8
III
UN1789
HYDROCHLORIC ACID SOLUTION
8
III
UN1789
HYDROCHLORIC ACID SOLUTION
8
III
15. Regulatory information
International Inventories
Component
Water
Hydrochloric acid
TSCA
X
X
DSL
X
X
NDSL EINECS ELINCS
231-791-2
231-595-7

NLP
PICCS
X
X
ENCS
X
AICS
X
X
IECSC
X
X
KECL
X
X
Legend:
X – Listed
E – Indicates a substance that is the subject of a Section 5(e) Consent order under TSCA.
F – Indicates a substance that is the subject of a Section 5(f) Rule under TSCA.
N – Indicates a polymeric substance containing no free-radical initiator in its inventory name but is considered to cover the designated
polymer made with any free-radical initiator regardless of the amount used.
P – Indicates a commenced PMN substance
R – Indicates a substance that is the subject of a Section 6 risk management rule under TSCA.
S – Indicates a substance that is identified in a proposed or final Significant New Use Rule
T – Indicates a substance that is the subject of a Section 4 test rule under TSCA.
XU – Indicates a substance exempt from reporting under the Inventory Update Rule, i.e. Partial Updating of the TSCA Inventory Data Base
Production and Site Reports (40 CFR 710(B).
Y1 – Indicates an exempt polymer that has a number-average molecular weight of 1,000 or greater.
Y2 – Indicates an exempt polymer that is a polyester and is made only from reactants included in a specified list of low concern reactants
that comprises one of the eligibility criteria for the exemption rule.
U.S. Federal Regulations
Not applicable
TSCA 12(b)
SARA 313
Component
CAS-No
Weight %
Hydrochloric acid
7647-01-0
3.65
SARA 311/312 Hazard Categories
CWA (Clean Water Act)
Component
Hydrochloric acid
Clean Air Act
Component
Hydrochloric acid
SARA 313 – Threshold
Values %
1.0
See section 2 for more information
CWA – Hazardous
Substances
X
CWA – Reportable
Quantities
5000 lb
HAPS Data
X
CWA – Toxic Pollutants CWA – Priority Pollutants

Class 1 Ozone Depletors

Class 2 Ozone Depletors

______________________________________________________________________________________________
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Revision Date 18-Jan-2018
Hydrochloric acid solution, 1N
______________________________________________________________________________________________
OSHA Occupational Safety and Health Administration
Specifically Regulated Chemicals

Component
Hydrochloric acid
Highly Hazardous Chemicals
TQ: 5000 lb
This material, as supplied, contains one or more substances regulated as a hazardous
substance under the Comprehensive Environmental Response Compensation and Liability
Act (CERCLA) (40 CFR 302)
CERCLA
Component
Hydrochloric acid
California Proposition 65
U.S. State Right-to-Know
Regulations
Component
Water
Hydrochloric acid
Hazardous Substances RQs
5000 lb
CERCLA EHS RQs
5000 lb
This product does not contain any Proposition 65 chemicals
Massachusetts
X
New Jersey
X
Pennsylvania
X
X
Illinois
X
Rhode Island
X
U.S. Department of Transportation
Reportable Quantity (RQ):
DOT Marine Pollutant
DOT Severe Marine Pollutant
Y
N
N
U.S. Department of Homeland Security
This product contains the following DHS chemicals:
Component
Hydrochloric acid
DHS Chemical Facility Anti-Terrorism Standard
0 lb STQ (anhydrous); 11250 lb STQ (37% concentration or
greater)
Other International Regulations
Mexico – Grade
No information available
Prepared By
Regulatory Affairs
Thermo Fisher Scientific
Email: EMSDS.RA@thermofisher.com
Creation Date
Revision Date
Print Date
Revision Summary
15-Feb-2010
18-Jan-2018
18-Jan-2018
This document has been updated to comply with the US OSHA HazCom 2012 Standard
replacing the current legislation under 29 CFR 1910.1200 to align with the Globally
Harmonized System of Classification and Labeling of Chemicals (GHS).
16. Other information
Disclaimer
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the
date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage,
transportation, disposal and release and is not to be considered a warranty or quality specification. The information
relates only to the specific material designated and may not be valid for such material used in combination with any other
materials or in any process, unless specified in the text
End of SDS
______________________________________________________________________________________________
Page 7 / 7
SIGMA-ALDRICH
sigma-aldrich.com
SAFETY DATA SHEET
Version 5.8
Revision Date 09/23/2016
Print Date 02/25/2018
1. PRODUCT AND COMPANY IDENTIFICATION
1.1
1.2
Product identifiers
Product name
:
Reagent alcohol
Product Number
Brand
:
:
362808
Aldrich
CAS-No.
:
64-17-5
Relevant identified uses of the substance or mixture and uses advised against
Identified uses
1.3
1.4
:
Laboratory chemicals, Synthesis of substances
Details of the supplier of the safety data sheet
Company
:
Sigma-Aldrich
3050 Spruce Street
SAINT LOUIS MO 63103
USA
Telephone
Fax
:
:
+1 800-325-5832
+1 800-325-5052
Emergency telephone number
Emergency Phone #
:
+1-703-527-3887 (CHEMTREC)
2. HAZARDS IDENTIFICATION
2.1
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Flammable liquids (Category 2), H225
Acute toxicity, Oral (Category 4), H302
Eye irritation (Category 2A), H319
Specific target organ toxicity – single exposure (Category 1), H370
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2
GHS Label elements, including precautionary statements
Pictogram
Signal word
Danger
Hazard statement(s)
H225
H302
H319
H370
Highly flammable liquid and vapour.
Harmful if swallowed.
Causes serious eye irritation.
Causes damage to organs.
Precautionary statement(s)
P210
P233
P240
P241
P242
Keep away from heat/sparks/open flames/hot surfaces. No smoking.
Keep container tightly closed.
Ground/bond container and receiving equipment.
Use explosion-proof electrical/ ventilating/ lighting/ equipment.
Use only non-sparking tools.
Aldrich – 362808
Page 1 of 11
P243
P260
P264
P270
P280
P301 + P312 + P330
Take precautionary measures against static discharge.
Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
Wash skin thoroughly after handling.
Do not eat, drink or smoke when using this product.
Wear protective gloves/ eye protection/ face protection.
IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
Rinse mouth.
IF ON SKIN (or hair): Take off immediately all contaminated clothing.
Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
IF exposed: Call a POISON CENTER or doctor/ physician.
If eye irritation persists: Get medical advice/ attention.
In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to
extinguish.
Store in a well-ventilated place. Keep cool.
Store locked up.
Dispose of contents/ container to an approved waste disposal plant.
P303 + P361 + P353
P305 + P351 + P338
P307 + P311
P337 + P313
P370 + P378
P403 + P235
P405
P501
2.3
Hazards not otherwise classified (HNOC) or not covered by GHS – none
3. COMPOSITION/INFORMATION ON INGREDIENTS
3.2
Mixtures
Synonyms
:
Absolute alcohol
Ethyl alcohol, Reagent alcohol
Formula
Molecular weight
:
:
C2H6O
46.07 g/mol
Hazardous components
Component
Classification
Concentration
Ethanol
CAS-No.
EC-No.
Index-No.
64-17-5
200-578-6
603-002-00-5
Flam. Liq. 2; Eye Irrit. 2A;
H225, H319
>= 90 – = 5 – < 10 % 2-Propanol CAS-No. EC-No. Index-No. 67-63-0 200-661-7 603-117-00-0 Flam. Liq. 2; Eye Irrit. 2A; STOT SE 3; H225, H319, H336 >= 5 – < 10 % For the full text of the H-Statements mentioned in this Section, see Section 16. 4. FIRST AID MEASURES 4.1 Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. Aldrich - 362808 Page 2 of 11 In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. 4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 4.3 Indication of any immediate medical attention and special treatment needed No data available 5. FIREFIGHTING MEASURES 5.1 Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. 5.2 Special hazards arising from the substance or mixture No data available 5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary. 5.4 Further information Use water spray to cool unopened containers. 6. ACCIDENTAL RELEASE MEASURES 6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8. 6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. 6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13). 6.4 Reference to other sections For disposal see section 13. 7. HANDLING AND STORAGE 7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Use explosion-proof equipment.Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2. 7.2 Conditions for safe storage, including any incompatibilities Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Moisture sensitive. Handle and store under inert gas. 7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated Aldrich - 362808 Page 3 of 11 8. EXPOSURE CONTROLS/PERSONAL PROTECTION 8.1 Control parameters Components with workplace control parameters Component CAS-No. Value Control parameters Ethanol 64-17-5 TWA 1,000.000000 ppm Remarks Methanol 67-56-1 Basis USA. ACGIH Threshold Limit Values (TLV) Upper Respiratory Tract irritation Confirmed animal carcinogen with unknown relevance to humans TWA 1,000 ppm USA. OSHA - TABLE Z-1 Limits for 1,900 mg/m3 Air Contaminants - 1910.1000 TWA 1,000 ppm USA. Occupational Exposure Limits 1,900 mg/m3 (OSHA) - Table Z-1 Limits for Air Contaminants The value in mg/m3 is approximate. TWA 1,000.000000 USA. Occupational Exposure Limits ppm (OSHA) - Table Z-1 Limits for Air 1,900.000000 Contaminants mg/m3 The value in mg/m3 is approximate. TWA 1,000.000000 USA. NIOSH Recommended ppm Exposure Limits 1,900.000000 mg/m3 STEL 1,000.000000 USA. ACGIH Threshold Limit Values ppm (TLV) Upper Respiratory Tract irritation Confirmed animal carcinogen with unknown relevance to humans TWA 200.000000 USA. ACGIH Threshold Limit Values ppm (TLV) Headache Nausea Dizziness Eye damage Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Danger of cutaneous absorption STEL 250.000000 USA. ACGIH Threshold Limit Values ppm (TLV) Headache Nausea Dizziness Eye damage Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Danger of cutaneous absorption TWA 200.000000 USA. NIOSH Recommended ppm Exposure Limits 260.000000 mg/m3 Potential for dermal absorption Aldrich - 362808 Page 4 of 11 ST 250.000000 USA. NIOSH Recommended ppm Exposure Limits 325.000000 mg/m3 Potential for dermal absorption TWA 200.000000 USA. Occupational Exposure Limits ppm (OSHA) - Table Z-1 Limits for Air 260.000000 Contaminants mg/m3 The value in mg/m3 is approximate. TWA 200 ppm USA. ACGIH Threshold Limit Values (TLV) Headache Nausea Dizziness Eye damage Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Danger of cutaneous absorption STEL 250 ppm USA. ACGIH Threshold Limit Values (TLV) Headache Nausea Dizziness Eye damage Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Danger of cutaneous absorption TWA 200 ppm USA. NIOSH Recommended 260 mg/m3 Exposure Limits Potential for dermal absorption ST 250 ppm USA. NIOSH Recommended 325 mg/m3 Exposure Limits Potential for dermal absorption TWA 200 ppm USA. Occupational Exposure Limits 260 mg/m3 (OSHA) - Table Z-1 Limits for Air Contaminants The value in mg/m3 is approximate. STEL 250 ppm USA. OSHA - TABLE Z-1 Limits for 325 mg/m3 Air Contaminants - 1910.1000 Skin notation TWA 200 ppm USA. OSHA - TABLE Z-1 Limits for 260 mg/m3 Air Contaminants - 1910.1000 Skin notation C 1,000 ppm California permissible exposure limits for chemical contaminants (Title 8, Article 107) Skin PEL 200 ppm California permissible exposure 260 mg/m3 limits for chemical contaminants (Title 8, Article 107) Skin STEL 250 ppm California permissible exposure 325 mg/m3 limits for chemical contaminants (Title 8, Article 107) Skin Aldrich - 362808 Page 5 of 11 2-Propanol 67-63-0 TWA 200.000000 ppm USA. ACGIH Threshold Limit Values (TLV) Central Nervous System impairment Upper Respiratory Tract irritation Eye irritation Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Not classifiable as a human carcinogen TWA 200 ppm USA. ACGIH Threshold Limit Values (TLV) Central Nervous System impairment Upper Respiratory Tract irritation Eye irritation Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Not classifiable as a human carcinogen STEL 400 ppm USA. ACGIH Threshold Limit Values (TLV) Central Nervous System impairment Upper Respiratory Tract irritation Eye irritation Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Not classifiable as a human carcinogen STEL 400.000000 USA. ACGIH Threshold Limit Values ppm (TLV) Central Nervous System impairment Upper Respiratory Tract irritation Eye irritation Substances for which there is a Biological Exposure Index or Indices (see BEI® section) Not classifiable as a human carcinogen TWA 400.000000 USA. Occupational Exposure Limits ppm (OSHA) - Table Z-1 Limits for Air 980.000000 Contaminants mg/m3 The value in mg/m3 is approximate. TWA 400.000000 USA. NIOSH Recommended ppm Exposure Limits 980.000000 mg/m3 ST 500.000000 USA. NIOSH Recommended ppm Exposure Limits 1,225.000000 mg/m3 PEL 400 ppm California permissible exposure 980 mg/m3 limits for chemical contaminants (Title 8, Article 107) STEL 500 ppm California permissible exposure 1,225 mg/m3 limits for chemical contaminants (Title 8, Article 107) Biological occupational exposure limits Component CAS-No. Parameters Methanol Aldrich - 362808 67-56-1 Methanol Value Biological specimen Basis 15.0000 mg/l Urine ACGIH - Biological Exposure Indices (BEI) Page 6 of 11 Remarks 2-Propanol 8.2 67-63-0 End of shift (As soon as possible after exposure ceases) Methanol 15 mg/l Urine ACGIH - Biological Exposure Indices (BEI) End of shift (As soon as possible after exposure ceases) Acetone 40.0000 Urine ACGIH - Biological mg/l Exposure Indices (BEI) End of shift at end of workweek Exposure controls Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Personal protective equipment Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Full contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 480 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.2 mm Break through time: 30 min Material tested:Dermatril® P (KCL 743 / Aldrich Z677388, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multipurpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. 9. PHYSICAL AND CHEMICAL PROPERTIES 9.1 Information on basic physical and chemical properties a) Appearance Form: liquid b) Odour No data available Aldrich - 362808 Page 7 of 11 9.2 c) Odour Threshold No data available d) pH No data available e) Melting point/freezing point Melting point/range: -130 °C (-202 °F) f) Initial boiling point and boiling range 78 °C (172 °F) at 1,013 hPa (760 mmHg) g) Flash point 9 °C (48 °F) - closed cup h) Evaporation rate No data available i) Flammability (solid, gas) No data available j) Upper/lower flammability or explosive limits Upper explosion limit: 24.5 %(V) Lower explosion limit: 3.3 %(V) k) Vapour pressure 59.5 hPa (44.6 mmHg) at 20 °C (68 °F) l) Vapour density No data available m) Relative density 0.785 g/cm3 n) Water solubility No data available o) Partition coefficient: noctanol/water No data available p) Auto-ignition temperature 362 °C (684 °F) q) Decomposition temperature No data available r) Viscosity No data available s) Explosive properties No data available t) Oxidizing properties No data available Other safety information No data available 10. STABILITY AND REACTIVITY 10.1 Reactivity No data available 10.2 Chemical stability Stable under recommended storage conditions. 10.3 Possibility of hazardous reactions Vapours may form explosive mixture with air. 10.4 Conditions to avoid Heat, flames and sparks. 10.5 Incompatible materials Aluminium, Acids, Oxidizing agents, Alkali metals, Halogenated compounds, Ammonia, Acid chlorides, Acid anhydrides, Reducing agents, Peroxides 10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides Other decomposition products - No data available In the event of fire: see section 5 Aldrich - 362808 Page 8 of 11 11. TOXICOLOGICAL INFORMATION 11.1 Information on toxicological effects Acute toxicity No data available Inhalation: No data available Dermal: No data available No data available Skin corrosion/irritation No data available Serious eye damage/eye irritation No data available Respiratory or skin sensitisation No data available Germ cell mutagenicity No data available Carcinogenicity IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. NTP: No component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP. OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA. Reproductive toxicity No data available No data available Specific target organ toxicity - single exposure No data available Specific target organ toxicity - repeated exposure No data available Aspiration hazard No data available Additional Information RTECS: Not available To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated., Central nervous system depression, Gastrointestinal disturbance, Nausea, Dizziness, Headache, narcosis, May cause convulsions. Stomach - Irregularities - Based on Human Evidence Kidney - Irregularities - Based on Human Evidence Stomach - Irregularities - Based on Human Evidence (Ethanol) Stomach - Irregularities - Based on Human Evidence (Methanol) Kidney - Irregularities - Based on Human Evidence (2-Propanol) 12. ECOLOGICAL INFORMATION 12.1 Toxicity No data available 12.2 Persistence and degradability No data available Aldrich - 362808 Page 9 of 11 12.3 Bioaccumulative potential No data available 12.4 Mobility in soil No data available 12.5 Results of PBT and vPvB assessment PBT/vPvB assessment not available as chemical safety assessment not required/not conducted 12.6 Other adverse effects No data available 13. DISPOSAL CONSIDERATIONS 13.1 Waste treatment methods Product Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Contaminated packaging Dispose of as unused product. 14. TRANSPORT INFORMATION DOT (US) UN number: 1170 Class: 3 Proper shipping name: Ethanol solutions Reportable Quantity (RQ): Packing group: II Poison Inhalation Hazard: No IMDG UN number: 1170 Class: 3 Proper shipping name: ETHANOL SOLUTION Packing group: II IATA UN number: 1170 Class: 3 Proper shipping name: Ethanol solution Packing group: II EMS-No: F-E, S-D 15. REGULATORY INFORMATION SARA 302 Components No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302. SARA 313 Components The following components are subject to reporting levels established by SARA Title III, Section 313: CAS-No. Revision Date Methanol 67-56-1 2007-07-01 2-Propanol 67-63-0 1987-01-01 SARA 311/312 Hazards Fire Hazard, Acute Health Hazard, Chronic Health Hazard Massachusetts Right To Know Components Ethanol Methanol 2-Propanol CAS-No. 64-17-5 67-56-1 67-63-0 Revision Date 2007-03-01 2007-07-01 1987-01-01 CAS-No. 64-17-5 67-56-1 67-63-0 Revision Date 2007-03-01 2007-07-01 1987-01-01 Pennsylvania Right To Know Components Ethanol Methanol 2-Propanol Aldrich - 362808 Page 10 of 11 New Jersey Right To Know Components Ethanol Methanol 2-Propanol California Prop. 65 Components WARNING: This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. Methanol CAS-No. 64-17-5 67-56-1 67-63-0 Revision Date 2007-03-01 2007-07-01 1987-01-01 CAS-No. 67-56-1 Revision Date 2012-03-16 16. OTHER INFORMATION Full text of H-Statements referred to under sections 2 and 3. Acute Tox. Eye Irrit. Flam. Liq. H225 H301 + H311 + H331 H302 H319 H336 H370 STOT SE Acute toxicity Eye irritation Flammable liquids Highly flammable liquid and vapour. Toxic if swallowed, in contact with skin or if inhaled Harmful if swallowed. Causes serious eye irritation. May cause drowsiness or dizziness. Causes damage to organs. Specific target organ toxicity - single exposure HMIS Rating Health hazard: Chronic Health Hazard: Flammability: Physical Hazard 2 * 3 0 NFPA Rating Health hazard: Fire Hazard: Reactivity Hazard: 2 3 0 Further information Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale. Preparation Information Sigma-Aldrich Corporation Product Safety – Americas Region 1-800-521-8956 Version: 5.8 Aldrich - 362808 Revision Date: 09/23/2016 Print Date: 02/25/2018 Page 11 of 11 SAFETY DATA SHEET Creation Date 15-Feb-2010 Revision Date 18-Jan-2018 Revision Number 3 1. Identification Product Name Hydrochloric acid solution, 1N Cat No. : SA55; S748561 Synonyms Muriatic acid solution; Hydrogen chloride solution (Certified) Recommended Use Uses advised against Laboratory chemicals. Not for food, drug, pesticide or biocidal product use Details of the supplier of the safety data sheet Company Fisher Scientific One Reagent Lane Fair Lawn, NJ 07410 Tel: (201) 796-7100 Emergency Telephone Number CHEMTRECÒ, Inside the USA: 800-424-9300 CHEMTRECÒ, Outside the USA: 001-703-527-3887 2. Hazard(s) identification Classification This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) Corrosive to metals Skin Corrosion/irritation Serious Eye Damage/Eye Irritation Category 1 Category 2 Category 1 Label Elements Signal Word Danger Hazard Statements May be corrosive to metals Causes skin irritation Causes serious eye damage ______________________________________________________________________________________________ Page 1 / 7 Revision Date 18-Jan-2018 Hydrochloric acid solution, 1N ______________________________________________________________________________________________ Precautionary Statements Prevention Keep only in original container Wear eye/face protection Wear protective gloves Wash face, hands and any exposed skin thoroughly after handling Skin IF ON SKIN: Wash with plenty of soap and water Take off contaminated clothing and wash before reuse If skin irritation occurs: Get medical advice/attention Eyes IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing Immediately call a POISON CENTER or doctor/physician Storage Store in corrosive resistant polypropylene container with a resistant inliner Disposal Dispose of contents/container to an approved waste disposal plant Hazards not otherwise classified (HNOC) None identified 3. Composition/Information on Ingredients Component Water Hydrochloric acid CAS-No 7732-18-5 7647-01-0 Weight % 96.35 3.65 4. First-aid measures General Advice If symptoms persist, call a physician. Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required. Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Obtain medical attention. Inhalation Move to fresh air. If breathing is difficult, give oxygen. Obtain medical attention. Ingestion Do not induce vomiting. Obtain medical attention. Most important symptoms and effects Notes to Physician May cause skin irritation and/or dermatitis. Suitable Extinguishing Media Substance is nonflammable; use agent most appropriate to extinguish surrounding fire. Unsuitable Extinguishing Media No information available Treat symptomatically 5. Fire-fighting measures Flash Point Method - Not applicable No information available No information available Autoignition Temperature Explosion Limits No data available Upper No data available Lower Sensitivity to Mechanical Impact No information available ______________________________________________________________________________________________ Page 2 / 7 Revision Date 18-Jan-2018 Hydrochloric acid solution, 1N ______________________________________________________________________________________________ Sensitivity to Static Discharge No information available Specific Hazards Arising from the Chemical Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Keep product and empty container away from heat and sources of ignition. Hazardous Combustion Products Hydrogen chloride gas Thermal decomposition can lead to release of irritating gases and vapors Protective Equipment and Precautions for Firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. NFPA Health 2 Flammability 0 Instability 0 Physical hazards N/A 6. Accidental release measures Use personal protective equipment. Ensure adequate ventilation. Do not get in eyes, on skin, or on clothing. Avoid release to the environment. See Section 12 for additional ecological information. Personal Precautions Environmental Precautions Methods for Containment and Clean Soak up with inert absorbent material. Keep in suitable, closed containers for disposal. Up 7. Handling and storage Handling Wear personal protective equipment. Ensure adequate ventilation. Do not get in eyes, on skin, or on clothing. Avoid ingestion and inhalation. Storage Keep containers tightly closed in a dry, cool and well-ventilated place. Corrosives area. 8. Exposure controls / personal protection Exposure Guidelines Component Hydrochloric acid ACGIH TLV Ceiling: 2 ppm OSHA PEL Ceiling: 5 ppm Ceiling: 7 mg/m3 (Vacated) Ceiling: 5 ppm (Vacated) Ceiling: 7 mg/m3 NIOSH IDLH IDLH: 50 ppm Ceiling: 5 ppm Ceiling: 7 mg/m3 Mexico OEL (TWA) Ceiling: 5 ppm Ceiling: 7 mg/m3 Legend ACGIH - American Conference of Governmental Industrial Hygienists NIOSH IDLH: The National Institute for Occupational Safety and Health Immediately Dangerous to Life or Health Engineering Measures Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations and safety showers are close to the workstation location. Personal Protective Equipment Eye/face Protection Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin and body protection Wear appropriate protective gloves and clothing to prevent skin exposure. Respiratory Protection Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard ______________________________________________________________________________________________ Page 3 / 7 Revision Date 18-Jan-2018 Hydrochloric acid solution, 1N ______________________________________________________________________________________________ EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Handle in accordance with good industrial hygiene and safety practice. Hygiene Measures 9. Physical and chemical properties Liquid Clear pungent No information available 1.1 (0.1N) 0 °C / 32 °F 100 °C / 212 °F Not applicable No information available Not applicable Physical State Appearance Odor Odor Threshold pH Melting Point/Range Boiling Point/Range Flash Point Evaporation Rate Flammability (solid,gas) Flammability or explosive limits Upper Lower Vapor Pressure Vapor Density Specific Gravity Solubility Partition coefficient; n-octanol/water Autoignition Temperature Decomposition Temperature Viscosity Molecular Formula Molecular Weight No data available No data available No information available No information available 1.0 - 1.2 Soluble in water No data available No information available No information available No information available HCl 36.46 10. Stability and reactivity Reactive Hazard None known, based on information available Stability Stable under normal conditions. Conditions to Avoid Incompatible products. Excess heat. Incompatible Materials Metals, Oxidizing agents, Reducing agents, Aldehydes Hazardous Decomposition Products Hydrogen chloride gas, Thermal decomposition can lead to release of irritating gases and vapors Hazardous Polymerization Hazardous polymerization does not occur. Hazardous Reactions None under normal processing. 11. Toxicological information Acute Toxicity Product Information Oral LD50 Dermal LD50 Vapor LC50 Component Information Component Water Hydrochloric acid Based on ATE data, the classification criteria are not met. ATE > 2000 mg/kg.
Based on ATE data, the classification criteria are not met. ATE > 2000 mg/kg.
Based on ATE data, the classification criteria are not met. ATE > 20 mg/l.
LD50 Oral
238 – 277 mg/kg ( Rat )
LD50 Dermal
Not listed
> 5010 mg/kg ( Rabbit )
LC50 Inhalation
Not listed
1.68 mg/L ( Rat ) 1 h
______________________________________________________________________________________________
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Hydrochloric acid solution, 1N
______________________________________________________________________________________________
No information available
Toxicologically Synergistic
Products
Delayed and immediate effects as well as chronic effects from short and long-term exposure
Irritation
Causes eye burns; Irritating to skin
Sensitization
No information available
Carcinogenicity
The table below indicates whether each agency has listed any ingredient as a carcinogen.
Component
CAS-No
IARC
Water
7732-18-5
Not listed
Hydrochloric acid
7647-01-0
Not listed
IARC: (International Agency for Research on Cancer)
NTP
ACGIH
OSHA
Not listed
Not listed
Not listed
Not listed
Not listed
Not listed
IARC: (International Agency for Research on Cancer)
Group 1 – Carcinogenic to Humans
Group 2A – Probably Carcinogenic to Humans
Group 2B – Possibly Carcinogenic to Humans
Mutagenic Effects
Mutagenic effects have occured in microorganisms.
Reproductive Effects
Experiments have shown reproductive toxicity effects on laboratory animals.
Developmental Effects
Developmental effects have occurred in experimental animals.
Teratogenicity
Teratogenic effects have occurred in experimental animals.
STOT – single exposure
STOT – repeated exposure
None known
None known
Aspiration hazard
No information available
Mexico
Not listed
Not listed
Symptoms / effects,both acute and No information available
delayed
Endocrine Disruptor Information
No information available
Other Adverse Effects
See actual entry in RTECS for complete information.
12. Ecological information
Ecotoxicity
.
Component
Hydrochloric acid
Freshwater Algae

Freshwater Fish
282 mg/L LC50 96 h
Gambusia affinis
mg/L LC50 48 h Leucscus
idus
Microtox

Water Flea
56mg/L EC50 72h Daphnia
Persistence and Degradability
Soluble in water Persistence is unlikely based on information available.
Bioaccumulation/ Accumulation
No information available.
Mobility
Will likely be mobile in the environment due to its water solubility.
Waste Disposal Methods
Chemical waste generators must determine whether a discarded chemical is classified as a
hazardous waste. Chemical waste generators must also consult local, regional, and
national hazardous waste regulations to ensure complete and accurate classification.
13. Disposal considerations
14. Transport information
DOT
UN-No
UN1789
______________________________________________________________________________________________
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Revision Date 18-Jan-2018
Hydrochloric acid solution, 1N
______________________________________________________________________________________________
HYDROCHLORIC ACID SOLUTION
8
III
Proper Shipping Name
Hazard Class
Packing Group
TDG
UN-No
Proper Shipping Name
Hazard Class
Packing Group
IATA
UN-No
Proper Shipping Name
Hazard Class
Packing Group
IMDG/IMO
UN-No
Proper Shipping Name
Hazard Class
Packing Group
UN1789
HYDROCHLORIC ACID SOLUTION
8
III
UN1789
HYDROCHLORIC ACID SOLUTION
8
III
UN1789
HYDROCHLORIC ACID SOLUTION
8
III
15. Regulatory information
International Inventories
Component
Water
Hydrochloric acid
TSCA
X
X
DSL
X
X
NDSL EINECS ELINCS
231-791-2
231-595-7

NLP
PICCS
X
X
ENCS
X
AICS
X
X
IECSC
X
X
KECL
X
X
Legend:
X – Listed
E – Indicates a substance that is the subject of a Section 5(e) Consent order under TSCA.
F – Indicates a substance that is the subject of a Section 5(f) Rule under TSCA.
N – Indicates a polymeric substance containing no free-radical initiator in its inventory name but is considered to cover the designated
polymer made with any free-radical initiator regardless of the amount used.
P – Indicates a commenced PMN substance
R – Indicates a substance that is the subject of a Section 6 risk management rule under TSCA.
S – Indicates a substance that is identified in a proposed or final Significant New Use Rule
T – Indicates a substance that is the subject of a Section 4 test rule under TSCA.
XU – Indicates a substance exempt from reporting under the Inventory Update Rule, i.e. Partial Updating of the TSCA Inventory Data Base
Production and Site Reports (40 CFR 710(B).
Y1 – Indicates an exempt polymer that has a number-average molecular weight of 1,000 or greater.
Y2 – Indicates an exempt polymer that is a polyester and is made only from reactants included in a specified list of low concern reactants
that comprises one of the eligibility criteria for the exemption rule.
U.S. Federal Regulations
Not applicable
TSCA 12(b)
SARA 313
Component
CAS-No
Weight %
Hydrochloric acid
7647-01-0
3.65
SARA 311/312 Hazard Categories
CWA (Clean Water Act)
Component
Hydrochloric acid
Clean Air Act
Component
Hydrochloric acid
SARA 313 – Threshold
Values %
1.0
See section 2 for more information
CWA – Hazardous
Substances
X
CWA – Reportable
Quantities
5000 lb
HAPS Data
X
CWA – Toxic Pollutants CWA – Priority Pollutants

Class 1 Ozone Depletors

Class 2 Ozone Depletors

______________________________________________________________________________________________
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Hydrochloric acid solution, 1N
______________________________________________________________________________________________
OSHA Occupational Safety and Health Administration
Specifically Regulated Chemicals

Component
Hydrochloric acid
Highly Hazardous Chemicals
TQ: 5000 lb
This material, as supplied, contains one or more substances regulated as a hazardous
substance under the Comprehensive Environmental Response Compensation and Liability
Act (CERCLA) (40 CFR 302)
CERCLA
Component
Hydrochloric acid
California Proposition 65
U.S. State Right-to-Know
Regulations
Component
Water
Hydrochloric acid
Hazardous Substances RQs
5000 lb
CERCLA EHS RQs
5000 lb
This product does not contain any Proposition 65 chemicals
Massachusetts
X
New Jersey
X
Pennsylvania
X
X
Illinois
X
Rhode Island
X
U.S. Department of Transportation
Reportable Quantity (RQ):
DOT Marine Pollutant
DOT Severe Marine Pollutant
Y
N
N
U.S. Department of Homeland Security
This product contains the following DHS chemicals:
Component
Hydrochloric acid
DHS Chemical Facility Anti-Terrorism Standard
0 lb STQ (anhydrous); 11250 lb STQ (37% concentration or
greater)
Other International Regulations
Mexico – Grade
No information available
Prepared By
Regulatory Affairs
Thermo Fisher Scientific
Email: EMSDS.RA@thermofisher.com
Creation Date
Revision Date
Print Date
Revision Summary
15-Feb-2010
18-Jan-2018
18-Jan-2018
This document has been updated to comply with the US OSHA HazCom 2012 Standard
replacing the current legislation under 29 CFR 1910.1200 to align with the Globally
Harmonized System of Classification and Labeling of Chemicals (GHS).
16. Other information
Disclaimer
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the
date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage,
transportation, disposal and release and is not to be considered a warranty or quality specification. The information
relates only to the specific material designated and may not be valid for such material used in combination with any other
materials or in any process, unless specified in the text
End of SDS
______________________________________________________________________________________________
Page 7 / 7
SAFETY DATA SHEET
Creation Date 20-Apr-2010
Revision Date 18-Jan-2018
Revision Number 4
1. Identification
Product Name
Propylene oxide
Cat No. :
O4332-1; NC0559300
CAS-No
Synonyms
75-56-9
1,2-Epoxypropane; Methyloxirane; Propene oxide (Reagent)
Recommended Use
Uses advised against
Laboratory chemicals.
Not for food, drug, pesticide or biocidal product use
Details of the supplier of the safety data sheet
Company
Fisher Scientific
One Reagent Lane
Fair Lawn, NJ 07410
Tel: (201) 796-7100
Emergency Telephone Number
CHEMTRECÒ, Inside the USA: 800-424-9300
CHEMTRECÒ, Outside the USA: 001-703-527-3887
2. Hazard(s) identification
Classification
This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200)
Flammable liquids
Acute oral toxicity
Acute dermal toxicity
Acute Inhalation Toxicity – Vapors
Serious Eye Damage/Eye Irritation
Germ Cell Mutagenicity
Carcinogenicity
Specific target organ toxicity (single exposure)
Target Organs – Respiratory system.
Category 1
Category 4
Category 3
Category 3
Category 2
Category 1B
Category 1B
Category 3
Label Elements
Signal Word
Danger
Hazard Statements
Extremely flammable liquid and vapor
Harmful if swallowed
Toxic in contact with skin
Causes serious eye irritation
Toxic if inhaled
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Revision Date 18-Jan-2018
Propylene oxide
______________________________________________________________________________________________
May cause respiratory irritation
May cause genetic defects
May cause cancer
Precautionary Statements
Prevention
Obtain special instructions before use
Do not handle until all safety precautions have been read and understood
Use personal protective equipment as required
Wash face, hands and any exposed skin thoroughly after handling
Do not eat, drink or smoke when using this product
Avoid breathing dust/fume/gas/mist/vapors/spray
Use only outdoors or in a well-ventilated area
Wear eye/face protection
Keep away from heat/sparks/open flames/hot surfaces. – No smoking
Keep container tightly closed
Ground/bond container and receiving equipment
Use explosion-proof electrical/ventilating/lighting/equipment
Use only non-sparking tools
Take precautionary measures against static discharge
Keep cool
Response
IF exposed or concerned: Get medical attention/advice
Inhalation
IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
Call a POISON CENTER or doctor/physician
Skin
Call a POISON CENTER or doctor/physician if you feel unwell
Wash contaminated clothing before reuse
IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower
Eyes
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
If eye irritation persists: Get medical advice/attention
Ingestion
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
Rinse mouth
Fire
In case of fire: Use CO2, dry chemical, or foam for extinction
Storage
Store locked up
Store in a well-ventilated place. Keep container tightly closed
Disposal
Dispose of contents/container to an approved waste disposal plant
Hazards not otherwise classified (HNOC)
Hazardous polymerization may occur
WARNING. Cancer – https://www.p65warnings.ca.gov/.
3. Composition/Information on Ingredients
Component
CAS-No
Weight %
______________________________________________________________________________________________
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Revision Date 18-Jan-2018
Propylene oxide
______________________________________________________________________________________________
Propylene oxide
75-56-9
>95
4. First-aid measures
General Advice
Show this safety data sheet to the doctor in attendance. Immediate medical attention is
required.
Eye Contact
In the case of contact with eyes, rinse immediately with plenty of water and seek medical
advice.
Skin Contact
Wash off immediately with plenty of water for at least 15 minutes. Immediate medical
attention is required.
Inhalation
Move to fresh air. If not breathing, give artificial respiration. Do not use mouth-to-mouth
method if victim ingested or inhaled the substance; give artificial respiration with the aid of a
pocket mask equipped with a one-way valve or other proper respiratory medical device.
Immediate medical attention is required.
Ingestion
Do not induce vomiting. Call a physician or Poison Control Center immediately.
Most important symptoms and
effects
Notes to Physician
. Inhalation of high vapor concentrations may cause symptoms like headache, dizziness,
tiredness, nausea and vomiting
Treat symptomatically
Suitable Extinguishing Media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Cool closed
containers exposed to fire with water spray.
Unsuitable Extinguishing Media
No information available
5. Fire-fighting measures
Flash Point
-37 °C / -34.6 °F
Method –
No information available
Autoignition Temperature
430 °C / 806 °F
Explosion Limits
37 vol %
Upper
2.3 vol %
Lower
Sensitivity to Mechanical Impact No information available
Sensitivity to Static Discharge No information available
Specific Hazards Arising from the Chemical
Extremely flammable. Containers may explode when heated. Vapors may form explosive mixtures with air. Vapors may travel to
source of ignition and flash back.
Hazardous Combustion Products
Carbon monoxide (CO) Carbon dioxide (CO2)
Protective Equipment and Precautions for Firefighters
As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full
protective gear. Thermal decomposition can lead to release of irritating gases and vapors.
NFPA
Health
3
Flammability
4
Instability
2
Physical hazards
N/A
6. Accidental release measures
Personal Precautions
Use personal protective equipment. Ensure adequate ventilation. Remove all sources of
ignition. Take precautionary measures against static discharges. Keep people away from
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Revision Date 18-Jan-2018
Propylene oxide
______________________________________________________________________________________________
and upwind of spill/leak. Evacuate personnel to safe areas.
Should not be released into the environment.
Environmental Precautions
Methods for Containment and Clean Soak up with inert absorbent material. Keep in suitable, closed containers for disposal.
Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment.
Up
7. Handling and storage
Handling
Wear personal protective equipment. Do not get in eyes, on skin, or on clothing. Use only
under a chemical fume hood. Do not breathe vapors or spray mist. Do not ingest. Keep
away from open flames, hot surfaces and sources of ignition. Use explosion-proof
equipment. Use only non-sparking tools. To avoid ignition of vapors by static electricity
discharge, all metal parts of the equipment must be grounded. Take precautionary
measures against static discharges.
Storage
Keep containers tightly closed in a dry, cool and well-ventilated place. Flammables area.
Keep away from heat and sources of ignition.
8. Exposure controls / personal protection
Exposure Guidelines
Component
Propylene oxide
ACGIH TLV
TWA: 2 ppm
OSHA PEL
(Vacated) TWA: 20 ppm
(Vacated) TWA: 50 mg/m3
TWA: 100 ppm
TWA: 240 mg/m3
NIOSH IDLH
IDLH: 400 ppm
Mexico OEL (TWA)
TWA: 20 ppm
TWA: 50 mg/m3
Legend
ACGIH – American Conference of Governmental Industrial Hygienists
OSHA – Occupational Safety and Health Administration
NIOSH IDLH: The National Institute for Occupational Safety and Health Immediately Dangerous to Life or Health
Engineering Measures
Use only under a chemical fume hood. Ensure that eyewash stations and safety showers
are close to the workstation location. Use explosion-proof
electrical/ventilating/lighting/equipment. Ensure adequate ventilation, especially in confined
areas.
Personal Protective Equipment
Eye/face Protection
Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA’s eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin and body protection
Long sleeved clothing.
Respiratory Protection
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard
EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if
exposure limits are exceeded or if irritation or other symptoms are experienced.
Hygiene Measures
Handle in accordance with good industrial hygiene and safety practice.
9. Physical and chemical properties
Physical State
Appearance
Odor
Odor Threshold
pH
Melting Point/Range
Liquid
Colorless
aromatic
No information available
No information available
-112 °C / -169.6 °F
______________________________________________________________________________________________
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Revision Date 18-Jan-2018
Propylene oxide
______________________________________________________________________________________________
34 °C / 93.2 °F
-37 °C / -34.6 °F
No information available
Not applicable
Boiling Point/Range
Flash Point
Evaporation Rate
Flammability (solid,gas)
Flammability or explosive limits
Upper
Lower
Vapor Pressure
Vapor Density
Specific Gravity
Solubility
Partition coefficient; n-octanol/water
Autoignition Temperature
Decomposition Temperature
Viscosity
Molecular Formula
Molecular Weight
37 vol %
2.3 vol %
590 mbar @ 20 °C
2.0
0.830
Soluble in water
No data available
430 °C / 806 °F
No information available
0.32 mPa s at 20 °C
C3 H6 O
58.08
10. Stability and reactivity
Reactive Hazard
Yes
Stability
Stable under normal conditions.
Conditions to Avoid
Incompatible products. Excess heat. Keep away from open flames, hot surfaces and
sources of ignition.
Incompatible Materials
Strong oxidizing agents, Acids, Bases, Amines, copper, Copper alloys, Peroxides
Hazardous Decomposition Products Carbon monoxide (CO), Carbon dioxide (CO2)
Hazardous Polymerization
Hazardous polymerization may occur.
Hazardous Reactions
None under normal processing.
11. Toxicological information
Acute Toxicity
Product Information
Component Information
Component
Propylene oxide
LD50 Oral
LD50 = 520 mg/kg ( Rat )
LD50 Dermal
LD50 = 1244 mg/kg ( Rabbit )
LC50 Inhalation
9.48 mg/L ( Rat ) 4 h
No information available
Toxicologically Synergistic
Products
Delayed and immediate effects as well as chronic effects from short and long-term exposure
Irritation
Irritating to eyes and respiratory system
Sensitization
No information available
Carcinogenicity
May cause cancer. The table below indicates whether each agency has listed any
ingredient as a carcinogen.
Component
Propylene oxide
CAS-No
75-56-9
IARC
Group 2B
IARC: (International Agency for Research on Cancer)
NTP
ACGIH
OSHA
Reasonably
A3
X
Anticipated
IARC: (International Agency for Research on Cancer)
Group 1 – Carcinogenic to Humans
Group 2A – Probably Carcinogenic to Humans
Mexico
A3
______________________________________________________________________________________________
Page 5 / 8
Revision Date 18-Jan-2018
Propylene oxide
______________________________________________________________________________________________
NTP: (National Toxicity Program)
ACGIH: (American Conference of Governmental Industrial
Hygienists)
Mexico – Occupational Exposure Limits – Carcinogens
Group 2B – Possibly Carcinogenic to Humans
NTP: (National Toxicity Program)
Known – Known Carcinogen
Reasonably Anticipated – Reasonably Anticipated to be a Human
Carcinogen
A1 – Known Human Carcinogen
A2 – Suspected Human Carcinogen
A3 – Animal Carcinogen
ACGIH: (American Conference of Governmental Industrial Hygienists)
Mexico – Occupational Exposure Limits – Carcinogens
A1 – Confirmed Human Carcinogen
A2 – Suspected Human Carcinogen
A3 – Confirmed Animal Carcinogen
A4 – Not Classifiable as a Human Carcinogen
A5 – Not Suspected as a Human Carcinogen
Mutagenic Effects
May cause heritable genetic damage
Reproductive Effects
No information available.
Developmental Effects
No information available.
Teratogenicity
No information available.
STOT – single exposure
STOT – repeated exposure
Respiratory system
None known
Aspiration hazard
No information available
Symptoms / effects,both acute and Inhalation of high vapor concentrations may cause symptoms like headache, dizziness,
tiredness, nausea and vomiting
delayed
Endocrine Disruptor Information
No information available
Other Adverse Effects
The toxicological properties have not been fully investigated.
12. Ecological information
Ecotoxicity
Do not empty into drains. .
Component
Propylene oxide
Freshwater Algae
EC50: = 240 mg/L, 96h
(Pseudokirchneriella
subcapitata)
Freshwater Fish
Microtox
LC50: = 215 mg/L, 96h static EC50 = 3300 mg/L 160 min
(Lepomis macrochirus)
Persistence and Degradability
Persistence is unlikely based on information available.
Bioaccumulation/ Accumulation
No information available.
Mobility
Will likely be mobile in the environment due to its volatility.
Component
Propylene oxide
Water Flea
EC50: = 350 mg/L, 48h
(Daphnia magna)
log Pow
0.08
13. Disposal considerations
Waste Disposal Methods
Chemical waste generators must determine whether a discarded chemical is classified as a
hazardous waste. Chemical waste generators must also consult local, regional, and
national hazardous waste regulations to ensure complete and accurate classification.
14. Transport information
DOT
UN-No
UN1280
______________________________________________________________________________________________
Page 6 / 8
Revision Date 18-Jan-2018
Propylene oxide
______________________________________________________________________________________________
PROPYLENE OXIDE
3
I
Proper Shipping Name
Hazard Class
Packing Group
TDG
UN-No
Proper Shipping Name
Hazard Class
Packing Group
IATA
UN-No
Proper Shipping Name
Hazard Class
Packing Group
IMDG/IMO
UN-No
Proper Shipping Name
Hazard Class
Packing Group
UN1280
PROPYLENE OXIDE
3
I
UN1280
PROPYLENE OXIDE
3
I
UN1280
PROPYLENE OXIDE
3
I
15. Regulatory information
All of the components in the product are on the following Inventory lists: X = listed
International Inventories
Component
Propylene oxide
TSCA
X
DSL
X
NDSL EINECS ELINCS
200-879-2

NLP
PICCS
X
ENCS
X
AICS
X
IECSC
X
KECL
X
Legend:
X – Listed
E – Indicates a substance that is the subject of a Section 5(e) Consent order under TSCA.
F – Indicates a substance that is the subject of a Section 5(f) Rule under TSCA.
N – Indicates a polymeric substance containing no free-radical initiator in its inventory name but is considered to cover the designated
polymer made with any free-radical initiator regardless of the amount used.
P – Indicates a commenced PMN substance
R – Indicates a substance that is the subject of a Section 6 risk management rule under TSCA.
S – Indicates a substance that is identified in a proposed or final Significant New Use Rule
T – Indicates a substance that is the subject of a Section 4 test rule under TSCA.
XU – Indicates a substance exempt from reporting under the Inventory Update Rule, i.e. Partial Updating of the TSCA Inventory Data Base
Production and Site Reports (40 CFR 710(B).
Y1 – Indicates an exempt polymer that has a number-average molecular weight of 1,000 or greater.
Y2 – Indicates an exempt polymer that is a polyester and is made only from reactants included in a specified list of low concern reactants
that comprises one of the eligibility criteria for the exemption rule.
U.S. Federal Regulations
Not applicable
TSCA 12(b)
SARA 313
Component
CAS-No
Weight %
Propylene oxide
75-56-9
>95
SARA 311/312 Hazard Categories
CWA (Clean Water Act)
Component
Propylene oxide
Clean Air Act
Component
Propylene oxide
SARA 313 – Threshold
Values %
0.1
See section 2 for more information
CWA – Hazardous
Substances
X
CWA – Reportable
Quantities
100 lb
HAPS Data
X
CWA – Toxic Pollutants CWA – Priority Pollutants

Class 1 Ozone Depletors

Class 2 Ozone Depletors

______________________________________________________________________________________________
Page 7 / 8
Revision Date 18-Jan-2018
Propylene oxide
______________________________________________________________________________________________
OSHA Occupational Safety and Health Administration
Not applicable
This material, as supplied, contains one or more substances regulated as a hazardous
substance under the Comprehensive Environmental Response Compensation and Liability
Act (CERCLA) (40 CFR 302)
CERCLA
Hazardous Substances RQs
100 lb
Component
Propylene oxide
California Proposition 65
Component
Propylene oxide
U.S. State Right-to-Know
Regulations
Component
Propylene oxide
CERCLA EHS RQs
100 lb
This product contains the following proposition 65 chemicals
CAS-No
75-56-9
California Prop. 65
Carcinogen
Massachusetts
X
New Jersey
X
Prop 65 NSRL

Pennsylvania
X
Illinois
X
Category
Carcinogen
Rhode Island
X
U.S. Department of Transportation
Reportable Quantity (RQ):
DOT Marine Pollutant
DOT Severe Marine Pollutant
Y
N
N
U.S. Department of Homeland Security
This product contains the following DHS chemicals:
Component
Propylene oxide
Other International Regulations
DHS Chemical Facility Anti-Terrorism Standard
7500 lb STQ
Mexico – Grade
Severe risk, Grade 4
Prepared By
Regulatory Affairs
Thermo Fisher Scientific
Email: EMSDS.RA@thermofisher.com
Creation Date
Revision Date
Print Date
Revision Summary
20-Apr-2010
18-Jan-2018
18-Jan-2018
This document has been updated to comply with the US OSHA HazCom 2012 Standard
replacing the current legislation under 29 CFR 1910.1200 to align with the Globally
Harmonized System of Classification and Labeling of Chemicals (GHS).
16. Other information
Disclaimer
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the
date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage,
transportation, disposal and release and is not to be considered a warranty or quality specification. The information
relates only to the specific material designated and may not be valid for such material used in combination with any other
materials or in any process, unless specified in the text
End of SDS
______________________________________________________________________________________________
Page 8 / 8

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